CURRICULUM VITAE
  • Name : SUZANA BINTI MAKPOL
  • Qualifications :
    • BSc. Hons (Clinical Biochemistry) (Universiti Kebangsaan Malaysia)
    • PhD (Medical Biochemistry) (Universiti Kebangsaan Malaysia)
  • Specialisation :
    • Medical Biochemistry (Cell Biology, Clinical Enzymology, Molecular Biology)
  • Areas of Research :
    • Cellular aging/replicative senescence - development of stress-induced premature aging (SIPS).
    • Molecular mechanism of antioxidant (tocotrienol, tocopherol, chlorella vulgaris, piper betle) in the prevention of cellular aging
    • Antioxidant and skin aging
  • Current Projects and Grants :
    • Development of in vitro reconstructed Asian skin equivalent model as testing system for industrial usage. UKM-FF-03-FRGS0163-2010. RM86,000. Active. (20 Ogos 2010-19 Ogos 2012).
    •  Anti aging mechanism of gamma-tocotrienol via apoptotic pathway in stress-induced premature senescence (SIPS) model. UKM-FF-03-FRGS0036-2010. RM77,000. Active. (15 Mac 2010-14 Mac 2012).
    • Molecular mechanism of gamma-tocotrienol in the prevention of cellular aging. UKM-FF-03-FRGS0043-2009. RM48,000. Active. (1 Nov.2009–31 Okt. 2011).
    • Effects of tocotrienol-rich fraction (TRF) against UV-induced skin aging in human diploid fibroblasts. FF-152-2010. RM10,000. Active. (31 Mei 2010–30 April 2011).
    • Determination of gamma-tocotrienol anti aging mechanism via apoptotic pathway in SIPS model. FF-313-2009. RM20,000. Active. (1 Nov. 2009–31 Okt. 2011).
    • Determination of gamma-tocotrienol anti aging mechanism via siRNA and regulation of cell cycle. FF-328-2009. RM20,000. Active. (1 Nov. 2009–31 Okt. 2011).
  • Selected Publications :
    • Wan Kamarulzaman Wan Safwani, Suzana Makpol, Somasundaram Sathapan, Kien Hui Chua. 2011. The changes of stemness biomarkers expression in human adipose-derived stem cells during long-term manipulation. Biotechnology and Applied Biochemistry 58(4): 261-270.
    • Saba Zuhair Hussein, Kamaruddin Mohd Yusoff, Suzana Makpol, Yasmin Anum Mohd Yusof. 2011. Antioxidant capacities and total phenolic contents increase with gamma irradiation in two types of Malaysian honey. Molecules 16: 6378-6395 (Open Access)
    • Siok-Fong Chin, Johari Ibrahim, Suzana Makpol, Noor Aini Abdul Hamid, Azian Abdul Latiff, Zaiton Zakaria, Musalmah Mazlan, Yasmin Anum Mohd Yusof, Aminuddin Abdul Karim, Wan Zurinah Wan Ngah. 2011. Tocotrienol-rich fraction supplementation improved lipid profile and oxidative status in healthy older adults.: A randomized controlled study. Nutrition & Metabolism 2011, 8: 42 (0pen Access).
    • Suzana Makpol, Linawati Durani, Kien Hui Chua, Yasmin Anum Mohd Yusof, Wan Zurinah Wan Ngah. 2011. Tocotrienol-rich fraction prevents cell cycle arrest and elongates telomere length in senescent human diploid fibroblasts. Journal of Biomedicine and Biotechnology, vol. 2011, article ID: 506171 (Open Access).
    • Yasmin Anum Mohd Yusof, Suhana Md Saad, Suzana Makpol, Nor Aripin Shamaan, Wan Zurinah Wan Ngah. 2010. Hot water extract of Chlorella vulgaris induced DNA damage and apoptosis. Clinics 65(12): 1371-1377.
    • Azalina Zainuddin, Kien Hui Chua, Norhazira Abdul Rahim, Suzana Makpol. 2010. Effects of experimental treatment on GAPDH mRNA expression as a housekeeping gene in human diploid fibroblasts. BMC Molecular Biology 11: 59 (Open Access).
    • Suzana Makpol, Azalina Zainuddin, Norhazira Abdul Rahim, Yasmin Anum Mohd Yusof, Wan Zurinah Wan Ngah 2010. Alpha-tocopherol Modulates Hydrogen Peroxide-Induced DNA Damage and Telomere Shortening of Human Skin Fibroblasts Derived from Differently Aged Individuals. Planta Medica 76(9): 869-875.
    • Suzana Makpol, Azrina Zainal Abidin, Khalilah Sairin, Musalmah Mazlan, Gapor Md. Top, Wan Zurinah Wan Ngah. 2010 g-Tocotrienol Prevents Oxidative Stress-Induced Telomere Shortening in Human Fibroblasts Derived from Different Aged Individuals. Oxidative Medicine and Cellular Longevity 3(1): Jan/Feb: 35-43.
    • Shailah Abdullah, Siti Amalina Zainal Abidin, Noor Azian Murad, Suzana Makpol, Wan Zurinah Wan Ngah, Yasmin Anum Mohd Yusof. 2010. Ginger Extract (Zingiber officinale) triggers apoptosis and G0/G1 cells arrest in HCT 116 and HT 29 colon cancer cell lines. African Journal of Biochemistry Research 4 (4): 134-142.
  • Contact Information :
    - Address
      DEPARTMENT OF BIOCHEMISTRY
      FACULTY OF MEDICINE
      Jalan Raja Muda Abdul Aziz
      50300 Kuala Lumpur
      Malaysia
    - Phone Number
      03-92897296
    - Fax Number
      03-26938037
    - E-mail